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　　More countries have joined Britain at restricting travel to the Egyptian resort of Sharm El-sheikh after a Russian passenger plane came down on Saturday killing all on board. France hasadvised against all but essential visits while Dutch and German airlines have suspended flights.Britain believes the plane was probably brought down by a bomb. The White House spokesmanJosh Ernest said the US had not ruled out terrorism as apossible cause. It is accurate to saythat the United States has not made our own determination about the cause of the incident,but based on what we know,and based on impart, and based on what's been publicly reportedin terms of claims of responsibility, we can't rule anything out including the possibility ofterrorist involvement.

　　Figures released by the European union   revealed that up to 3 million migrants could arrive in theEU by the end of 2017. In a separate report, the UN refugee agency said it expected people tocontinue arriving in Greece from Turkey at arate of 5000 a day. The BBC's Richard Galpin saysofficials on the island of Lesbos are struggling to cope. Here in Lesbos today, the head of theEuropean parliament Martin Schulz visited a refugee camp with the Greek Prime Minister AlexTsipras. They were greeted by protesters calling for an immediate action to prevent morepeople drowning during a short journey across the Aegean Sea from Turkey to the Greekislands. Both Mr. Schulz and Mr. Tsipras are deeply concerned about the death. And thenumbers arriving from Turkey are not dropping now despite the increasingly cold weather. Mr.Schulz said Turkey must agree to stand the flow of refugees and migrants from its shores asquickly as possible.

　　Mafia bosses, politicians and businessmen have appeared in court in Rome at the start of Italy'sbiggest anti-corruption trial for decades. They are accused of rigging contracts for publicservices over many years, even bringing the Italian capital's finances close to the point ofcollapse.

　　A one year old British girl has become the first person in the world to receive a pioneering genetherapy treatment that has cleared her off cancer. Leila Richiewas just three months old whenshe was diagnosed with aggressive leukemia. Here is our health reporter James Gallagher. Onthe day before Leila's first birthday, her family was told that all treatments had failed, and theirdaughter was going to die. But her parents were determined to try anything. And staff at thechildren's hospital were rapidly given permission to use an experimental therapy that hadbeen trialed only in mice. It uses cutting-edge genetic engineering to design immune cells thatcan hunt down Leukemia. A few weeks after the cells were injected, Leila started to recover.World news from the BBC.

　　Reports from Syria say that rebel groups have captured a town on the vital highway fromDamascus to Aleppo. Syrian activists sound the Rebels from cell say they have taken Morecwhich is north of Hama. On Wednesday, government forces said they had retaken control ofthe alternative route to Aleppo.

　　The charity Medecins Sans Frontier says its staff saw people being shot from the air as theytried to flee a hospital in Afghanistan that was hit by US airstrikes a month ago. In a review ofthe incident in Kunduz, MSF said its own personnel were hit while trying to reach safety. Itacknowledged that about 20 patients at the time were wounded Taliban. The charity's directorChristopher Stokes said it was hard to believe that the bombing had been a mistake. Reviewfrom inside the hospital is that this attack was conducted with a purpose to kill and destroy,and this was certainly my impression went on in Kunduz two weeks ago, but we still do notknow why, and we do not have a view from cockpit inside the plane, and we don't have theview from within the chain of command of the different forces either US or Afghanistan, so wewon't include that.

　　One of India's most wanted man has been deported from Indonesia. Rajendra Chhota Rajan,also known as little Rajan, was detained in Bali ten days ago. His arrest came after a tip offfrom the authorities in Australia where he had apparently been living under assumed identityfor 20 years. He is accused of multiple offenses, including murder, extortion and drugtrafficking.

　　Campaign advertisements for the Republican Party presidential contender Donald Trump arerunning for the first time on radio stations in three American states, Iowa, New Hampshire andSouth Carolina. They are the first adverts Mr.Trump has paid for since entering the race tobecome the Republican candidate in next year's election. He said the 300,000-dollarcampaign was part of his efforts to fend off his rivals. BBC news.